I am having what seems to be the same problem.
Just like Alex, I have a static page at root and posts on a separate page and this only started after 4.5 upgrade.
Disabling plugins, changing to default theme makes no difference. Disabling static page for root does fix it. Changing to any other static page still results in the redirect hang.
Unfortunately, Marius’ suggestion above does not apply. My site and wordpress URLs are entirely lowercase.
