i have this same problem, every-time i make anew page with Elementor, next day or sometimes within the hour, the page loses all its formating, and the text and images are all in a single column.
it has been doing it with the last 2 updates, version 1.5.1 and 1.5.2
i see you mention cache plug-ins as a possible cause. i have Autoptimize and W3 Total Cache installed, i will deactivate them an try one more time with Elementor.