I am having the same issue for several of my sites. Javascript functions that depend on Ajax are getting the 403 error when they try to access /wp-admin/admin-ajax.php
This is even happening in Learning Mode.
It doesn’t happen for IP addresses that bypass the rules (admin using my IP can access) and use any of the JS functions that call /wp-admin/admin-ajax.php, but general visitors cannot.
This is a serious issue for WordFence. At this point my client is leaning toward removing the plugin. I would think that with the amount of issues that I’m finding in my search, someone on the WordFence staff would spend some time to get this issue resolved instead of taking the standard tact that it must be a conflict with other plugins.