I have the same prob. Ran the automated upgrade. After it unpacked files I got a blank white screen.
According to my log files, the error is
[Thu Jun 17 15:35:11 2010] [error] [client zz] PHP Fatal error: Call to undefined function is_multisite() in /var/www/vhosts/smydomain.com/httpdocs/wp-includes/wp-db.php on line 505
I replaced the path with a fake domain as to not post my actual domain here.
this is BS.
I then tried to manually upgrade but to no avail. still doesn’t work. cannot log in to wp-admin to complete upgrade.. can’t do anything.. wtf?