Transients vs Object cache vs Global cache groups

  • Hello,

    I have a multisite with Buddypress, one main site and thousand of blogs created by users.

    I know that switch_to_blog is quite dangerous but I am not quite sure about the caching system should I use.

    I plan to instal W3 Total Cache, so Transients won’t be stored in the database.

    Should I use Transients API, wp_cache or wp_cache global groups? Or it will depend upon what I’m caching?

    And what cache system is the recommended for the server? APC? Memcache?

    Many thanks in advance for any light on this.

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