Hi there
We’re not aware of anything specific that would disable the Site Accelerator feature, but the most likely thing is probably a theme or plugin conflict.
I know it’s less than ideal, but could you please try the following:
– Temporarily deactivate all the site’s plugins except for Jetpack and clear your browser’s cache.
– If the setting then remains activated, then we’ll know that another plugin is conflicting here. You can re-enable your plugins one by one, checking in between, until you find the one causing the conflict. You can leave it disabled or reach out to the plugin developer for a fix.
If disabling plugins doesn’t help, it may be the theme.
– Temporarily switch your theme to a WordPress default theme like Twenty Twenty. Then test again. If the setting remains activated, then you know it’s a problem with the theme, and you can reach out to the theme developer for a fix.
If none of that helps, I’d suggest contacting your hosting provider to see if they have any other CDN in use that might be deactivating the Jetpack one.