Smilies sizes are all messed up

Most likely related to a new feature in WP4.2 that lets you add them in certain scenarios and that there is some at this point unknown CSS and/or js conflict between WP4.2 and current theme or an active plugin (wherever such is being output from). Please provide the site url for us to review. Without, this topic is too generic.

The url is https://toxid-lotus.net/

Your site is including an iframe from an external site:
//https://eepurl.com/IznhL

A check of that site at Sucuri shows it is running on a very outdated and insecure version of nginx.

https://sitecheck.sucuri.net/

Do you know what is including that?

I ended up installing a plugin that disables the emoji stuff and it fixed it.