Problem with Php version (4.4.7) and WordPress v3.0

I am working on rewrite rules
based on the following server and installation :
IIS6 Server
Php 4.4.7
IIRF v 1.2.15

First I would like to know if thi Php version is really optimum to run WordPress 3.0

Second if this configuration could compromise my permalinks settings, as it does not work, whatever I try.
Here is bellow my latest rule . This rule allow me to have a full correct and pretty permalink in my URL adress bar, but the blog does not appear anymore and instead gives me the following :

No input file specified.
+
The index of my blog comes out as 404…

MY REWRITE RULE :

# IsapiRewrite4.ini
RewriteCond %{REQUEST_FILENAME} !-f
RewriteCond %{REQUEST_FILENAME} !-d
RedirectRule ^/my-blog/index\.php/(.*)$ /my-blog/$1 [I,R=301]
RewriteRule ^/my-blog/(?!index\.php|wp-|xmlrpc)(.*)$ /my-blog/index.php/$1 [I,L]
#

Thank you…I am seriously in trouble…