Posts in multiple collumns

This can normally be done using widgets. Look for “recent posts with excerpts” – you might have to do some code modification to get it to do exactly what you want it to do, but that should get you started.

I don’t understand how that will fix my problem. That is a sidebar widget, how do I use it in the loop?

I would do this with 2 loops.

The first would query just 1 post and show it with appropriate CSS styles.

<?php query_posts('showposts=1'); ?>
<?php while (have_posts()) : the_post(); ?>
your stuff here
<?php endwhile; ?><?php endwhile; endif; ?>

The second would skip the first post

<?php query_posts('posts_per_page=4&offset=1'); ?>
<?php while (have_posts()) : the_post(); ?>
your stuff here
<?php endwhile; ?><?php endwhile; endif; ?>

Thanks for helping.

But when I try your code the page just goes blank. Here is my code:

<div id="articleContainer">
		<?php query_posts('showposts=1'); ?>
		<?php while (have_posts()) : the_post(); ?>
			<article id="bigPost" <?php post_class() ?> id="post-<?php the_ID(); ?>">
				<!-- check if the post has a Post Thumbnail assigned to it. -->
				<a href="<?php the_permalink() ?>"> <?php if ( has_post_thumbnail() ) { the_post_thumbnail('bigThumb'); } ?></a>
				<div class="postItems">
                	<h2 class="bigTitle"><a href="<?php the_permalink() ?>"><?php the_title(); ?></a></h2>
                    <div class="entry">
                    	 <?php the_content(); ?>
                    </div>
                    <div class="postMetaData">
                        <span id="meta" class="time"> <?php the_time('d/m/Y  g:ia') ?></span>
                        <span id="meta" class="comments"><?php comments_number( 'Ingen kommentarer', 'én kommentar', '% kommentarer' ); ?>.</span>
                        <span id="meta" class="category">Kategori: <?php the_category(', ') ?></span>
                    </div>
            	</div>
			</article> <!-- end bigPost -->
		<?php endwhile; ?><?php endwhile; endif; ?>
 </div> <!-- end articleContainer -->