One information: I disabled all other plugins, but the problem further occured.
Here is my Site Health Information:
### wp-core ###
version: 5.5
site_language: de_DE
user_language: de_DE
timezone: Europe/Berlin
permalink: /%postname%/
https_status: true
user_registration: 0
blog_public: 1
default_comment_status: open
multisite: false
user_count: 9
dotorg_communication: true
### wp-paths-sizes ###
wordpress_path: /srv/www/cleanthinking
wordpress_size: 3,53 GB (3790336420 bytes)
uploads_path: /srv/www/cleanthinking/wp-content/uploads
uploads_size: 1,46 GB (1571984138 bytes)
themes_path: /srv/www/cleanthinking/wp-content/themes
themes_size: 78,92 MB (82753316 bytes)
plugins_path: /srv/www/cleanthinking/wp-content/plugins
plugins_size: 85,54 MB (89691294 bytes)
database_size: 968,35 MB (1015385717 bytes)
total_size: 6,10 GB (6550150885 bytes)
### wp-active-theme ###
name: Publisher (publisher)
version: 7.7.0
author: BetterStudio
author_website: https://betterstudio.com/
parent_theme: none
theme_features: core-block-patterns, title-tag, html5, post-thumbnails, post-formats, automatic-feed-links, menus, editor-style, widgets
theme_path: /srv/www/cleanthinking/wp-content/themes/publisher
auto_update: Deaktiviert
### wp-themes-inactive (1) ###
Twenty Twenty: version: 1.5, author: WordPress-Team,Automatische Aktualisierungen deaktiviert
### wp-plugins-active (24) ###
404page – your smart custom 404 error page: version: 11.2.6, author: Peter Raschendorfer, Automatische Aktualisierung aktiviert
AAWP: version: 3.13, author: AAWP, Automatische Aktualisierung aktiviert
Akismet Anti-Spam: version: 4.1.6, author: Automattic, Automatische Aktualisierung aktiviert
AMP: version: 2.0.0, author: AMP Project Contributors, Automatische Aktualisierungen deaktiviert
Better Ads Manager: version: 1.19.4, author: BetterStudio, Automatische Aktualisierungen deaktiviert
Better Post Views: version: 1.6.0, author: BetterStudio, Automatische Aktualisierungen deaktiviert
Better Social Counter Widget: version: 1.13.1, author: BetterStudio, Automatische Aktualisierungen deaktiviert
Check Email: version: 0.6.1, author: MachoThemes, Automatische Aktualisierung aktiviert
Cookiebot | GDPR/CCPA Compliant Cookie Consent and Control: version: 3.7.1, author: Cybot A/S, Automatische Aktualisierung aktiviert
Custom Sidebars: version: 3.2.3, author: WPMU DEV, Automatische Aktualisierungen deaktiviert
Disable Feeds: version: 1.4.4, author: Samir Shah, BBpress support by Matthew Sigley, Automatische Aktualisierung aktiviert
Facebook Pixel: version: 1.6.0, author: Facebook, Automatische Aktualisierungen deaktiviert
Hummingbird Pro: version: 2.5.3, author: WPMU DEV, Automatische Aktualisierungen deaktiviert
Newsletter, SMTP, Email marketing and Subscribe forms by Sendinblue: version: 3.0.6, author: Sendinblue, Automatische Aktualisierung aktiviert
Smush Pro: version: 3.6.3, author: WPMU DEV, Automatische Aktualisierungen deaktiviert
SubHeading: version: 1.8.1, author: StvWhtly, Automatische Aktualisierung aktiviert
TablePress: version: 1.12, author: Tobias B?thge, Automatische Aktualisierung aktiviert
wp-worthy: version: 1.5.6.1, author: tiggersWelt.net, Automatische Aktualisierung aktiviert
WPBakery Page Builder: version: 6.2.0, author: Michael M – WPBakery.com, Automatische Aktualisierungen deaktiviert
WPMU DEV Dashboard: version: 4.10.0, author: WPMU DEV, Automatische Aktualisierungen deaktiviert
WP PayPal: version: 1.2.2.5, author: naa986, Automatische Aktualisierung aktiviert
Yoast Duplicate Post: version: 3.2.5, author: Enrico Battocchi & Team Yoast, Automatische Aktualisierung aktiviert
Yoast SEO: News: version: 12.6, author: Team Yoast, Automatische Aktualisierungen deaktiviert
Yoast SEO Premium: version: 14.8.1, author: Team Yoast, Automatische Aktualisierungen deaktiviert
### wp-media ###
image_editor: WP_Image_Editor_Imagick
imagick_module_version: 1673
imagemagick_version: ImageMagick 6.8.9-9 Q16 x86_64 2019-11-12 https://www.imagemagick.org
file_uploads: File uploads is turned off
post_max_size: 8M
upload_max_filesize: 2M
max_effective_size: 2 MB
max_file_uploads: 20
imagick_limits:
imagick::RESOURCETYPE_AREA: 63 GB
imagick::RESOURCETYPE_DISK: 1.844674407371E+19
imagick::RESOURCETYPE_FILE: 768
imagick::RESOURCETYPE_MAP: 63 GB
imagick::RESOURCETYPE_MEMORY: 31 GB
imagick::RESOURCETYPE_THREAD: 8
gd_version: 2.3.0
ghostscript_version: 9.26
### wp-server ###
server_architecture: Linux 4.4.0-169-generic x86_64
httpd_software: Apache
php_version: 7.4.6 64bit
php_sapi: fpm-fcgi
max_input_variables: 1000
time_limit: 30
memory_limit: 512M
max_input_time: 60
upload_max_size: 2M
php_post_max_size: 8M
curl_version: 7.47.0 OpenSSL/1.0.2g
suhosin: false
imagick_availability: true
pretty_permalinks: true
htaccess_extra_rules: true
### wp-database ###
extension: mysqli
server_version: 5.6.26-74.0
client_version: mysqlnd 7.4.6
### wp-constants ###
WP_HOME: undefined
WP_SITEURL: undefined
WP_CONTENT_DIR: /srv/www/cleanthinking/wp-content
WP_PLUGIN_DIR: /srv/www/cleanthinking/wp-content/plugins
WP_MAX_MEMORY_LIMIT: 256M
WP_DEBUG: true
WP_DEBUG_DISPLAY: true
WP_DEBUG_LOG: true
SCRIPT_DEBUG: false
WP_CACHE: true
CONCATENATE_SCRIPTS: undefined
COMPRESS_SCRIPTS: undefined
COMPRESS_CSS: undefined
WP_LOCAL_DEV: undefined
DB_CHARSET: utf8
DB_COLLATE: undefined
### wp-filesystem ###
wordpress: writable
wp-content: writable
uploads: writable
plugins: writable
themes: writable
mu-plugins: writable
### amp_wp ###
amp_mode_enabled: transitional
amp_reader_theme: legacy
amp_templates_enabled: post, page, attachment, is_singular, is_front_page, is_archive, is_search, is_404, is_category, is_tag
amp_serve_all_templates: false
amp_css_transient_caching_disabled: false
amp_css_transient_caching_threshold: 5000 transients per day
amp_css_transient_caching_sampling_range: 14 days
amp_css_transient_caching_transient_count: 1180
amp_css_transient_caching_time_series:
20200814: 467
20200815: 462
20200816: 431
20200817: 433
20200818: 422
20200819: 400
20200820: 397
20200821: 377
20200822: 353
20200823: 353
20200824: 354
20200825: 337
20200826: 335
20200827: 1176
amp_libxml_version: 2.9.10
`