Is this plugin WP Multisite friendly?

Yes as in; each site can have its own settings and the cache is nicely separated per site.

No as in; there is no network-wide admin-page (but you can easily enforce settings network wide with a couple of lines of code)

hope this clarifies,
frank

Thanx a lot man,
Have a great New Year
Cheers
TR

Have a great New Year

and you! ??

Do I install this other autoautoptimize as plugin?,

the network-wide code? that would typically be a separate plugin which you would indeed need to activate yes. haven’t tested this myself though ??

Thanx cheers