How to remove repeating posts from slider and area beside slider on homepage?

Hi,

My upcoming sports news site has five categories: 1. Football, 2. Hockey, 3. Baseball, 4. Basketball, and 5. Golf. I want to show a post from any one category in the Slider Area and one each from the rest of the four categories in each of the four boxes in the Area Beside Slider. How can I achieve this?

Also, I would really like that none of the posts that show up in the Slider Area and the Area Beside Slider gets repeated anywhere on the rest of the homepage. How can I do it?

Please suggest like I am a newbie.

Thanks, and I really look forward to hearing from you soon.