How to disable Moderation of Comments???

If you want to just disable the email alert then go to your Dashboard then click on Options then on Discussion then uncheck the box under the Email whenever section labeled a comment is held for moderation. If you want to disable comment moderation ( Not a good idea) you can also do that from the same page, just have a look around at the page.

Look at the various settings on the Admin Page->Options->Discussion.

Hmm.. i wanna disable it complete.. let peoples comment

We see your problem. Remove the tick from the “Comment author must have a previously approved comment” option on the Options > Discussion Options page.