Help Needed with a new Template

Hello All

I have been out of the business of webdesign for the last few years (I’m a server side developer now). I have designed a photoshop mock of the template I would like to use, but I am unsure how to chop it to get it working with WordPress and most especially making it compliant. It would be great if a kindly soul would be able to assist me? I would happily email a zip of the photoshop mock if you could just advise me what the main bits are and how to get it working with wordpress.