Thanks for your post and for your interest in the plugin. Configuring MLA really depends on your application objectives and which tasks you’d like help with.
For help with MLA’s shortcodes you can start with these earlier topics:
Basic newbie where to start
Confused Newbie
For help with admin mode tasks there are similar topics addressing how to use taxonomies, perform bulk edits, map IPTC/EXIF/XMP metadata to standard and custom field values and much more.
If you can provide more details about what you’d like to accomplish I can give you more specific guidance. Let me know how I can help.