Exclude Optimize JavaScript Code for IE8 only

theoretically: yes, hooking into the API (autoptimize_filter_noptimize) and returning true if the browser=IE8, but the (big) downside is that you would also have to tell you page caching mechanism (plugin or other) not to cache pages and not to return cached pages if useragent = IE8, which will make the load on your server higher.

so in reality I would not do that, but try to fix the JS errors instead somehow.

frank