Unfortunately, my searches to find a similar question and better answer from the forums from a few days ago is coming up empty.

From WP Security:

Okay, so this is the DoS issue with load-scripts.php and load-styles.php: Basically, the best mitigation for this is at the network level. Hosts and WAFs can rate limit this in a way that makes a lot more sense than anything WordPress can do. Caching would also be extremely useful in this case. Something that we _could_ do is limit the number of scripts that could be loaded at once with those, but the problem with that is all it does is reduce the load by some relatively marginal amount.