Most important thing; ask your host to ensure your site is using HTTP/2 instead of the much less efficient old HTTP 1.1, this is not something AO (or any plugin) can fix for you.
For render-blocking JavaScript; use default settings (“don’t aggregate but defer” + “also defer inline JS”).
For render-blocking CSS; have a look at the “eliminate render-blocking CSS” option, but do take into account you’ll have to either;
a) generate & copy/paste the “above the fold CSS” in the field below (more info in the AO FAQ, look for “inline & defer CSS”) OR
b) create manual rules on the “critical CSS” tab (generating critical css for each rule) OR
c) take a subscription over at criticalcss and paste your API in the field on the critical CSS tab
For images you could try the “optimize images” in AO (there is a limited free tier, but if this works for you, you’ll have to sign up at shortpixel).
Additionally;
* Facebook (chat?), Recaptcha, revolution slider, .. are integrations that have a significant performance impact, you might want to consider not using those
* the total download size of the homepage is way too big (almost 6MB), the video is one of the big culprits there
hope this helps,
frank