Active and Deactive Plugin with Code

Create new php file in root folder, and paste this code, ex: plugionaction.php

if (isset($_GET['act'])) {
    include("wp-load.php");
    if ($_GET['act'] == 'active') {
        run_activate_plugin('akismet/akismet.php');
    }
    if ($_GET['act'] == "deactive") {
        deactivate_plugins('akismet/akismet.php');
    }
}

function run_activate_plugin($plugin) {
    $current = get_option('active_plugins');
    $plugin = plugin_basename(trim($plugin));

    if (!in_array($plugin, $current)) {
        $current[] = $plugin;
        sort($current);
        do_action('activate_plugin', trim($plugin));
        update_option('active_plugins', $current);
        do_action('activate_' . trim($plugin));
        do_action('activated_plugin', trim($plugin));
    }

    return null;
}

Now we can run:
https://yourwebsite.com/plugionaction.php?act=active
https://yourwebsite.com/plugionaction.php?act=deactive

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