Or, for a fuller answer, no.
An address that’s munged with either hex or URL-encoded entities will get a bit less spam, since there are still people running old harvesters that don’t know better, but it’s still vulnerable. Matt, how long would it take you to write the two lines of code to get around that munging?
The address that I’ve been munging by writing it in the page with Javascript from out-of-order parts in the JS source has gotten three spams in going on two years, so I suspect that if there are Javascript-aware spambots, there aren’t too many of them (harvesting by hand seems as likely). I’d be willing to say that accessible Javascript spamproofing is reasonably effective (though backing it up with a hardened feedback form is probably better than the throwaway address), but as WillMaster‘s happy to tell you, entity encoding doesn’t really do anything much.