Installing the e-commerce plugin on my blog?

Hi out there.
I have a WP blog , but would also like to make a “webshop”
I am thinking of using the WP e-commerce plugin, but there are some questions that comes in to my mind.
In the blog I write about a spesific historichal song tradition.
The webshop will be of an absolutely different type. The “things” that i will sell from the shop will have NOTHING to do with the blog.
I feel that if I mix the two together,(blog and shop) it will start to look a little odd.
Is there some trix to use so that the shop will look seperated from the blog? (Looks like it stands alone)(For example a way so that the shop has its own “adress”?)
The best way I can explain it is that the shop is in the blog, but there are two didderent dors. one for the blog and one for the shop.
Any tips and trix would be of great help.

Best regards
captn-nemo