Site down!!! Please help: Fata Error

all of a sudden when I go to my site: https://www.getfamiliar.net i get these error messages:

Warning: require_once(/home/getfamiliar/getfamiliar.net/wp-config.php) [function.require-once]: failed to open stream: Permission denied in /home/getfamiliar/getfamiliar.net/wp-load.php on line 27

Fatal error: require_once() [function.require]: Failed opening required ‘/home/getfamiliar/getfamiliar.net/wp-config.php’ (include_path=’.:/usr/local/php5/lib/php:/usr/local/lib/php’) in /home/getfamiliar/getfamiliar.net/wp-load.php on line 27

What should i Do